Juvenile nasopharyngeal angiofibroma with orbital extension angiofibroma nasofaringeo juvenil con extension orbitaria. Another case of recurring nasopharyngeal angiofibroma with lateral extension to peterygomaxillary fossa and cheek removed successfully by transpalatal and. The process was diagnosed as a juvenile nasopharyngeal angiofibroma. Pdf imaging in the diagnosis of juvenile nasopharyngeal. Cellular angiofibroma of the nasopharynx is very rare, and the. Juvenile nasopharyngeal angiofibroma is a benign but locally invasive tumor accounting for about 0. Juvenile nasopharyngeal angiofibroma jna is a locally invasive benign tumor which almost exclusively originates in the posterior area of the nasal cavity. Juvenile nasopharyngeal angiofibroma jna springerlink. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that exhibits a predictable spreading pattern. If the inline pdf is not rendering correctly, you can download the pdf file here. Nasopharyngeal angiofibroma presents with symptoms of nasal obstruction and epistaxis. Pdf nasopharyngeal angiofibroma is a relatively rare benign, but locally aggresive tumor of the nasopharynx afflicting the adolescent males. Juvenile nasopharyngeal angiofibroma jna is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males.
Ppt journal juvenile nasopharynx angiofibroma free download as powerpoint presentation. Usually, the presenting symptom is a painless nasal obstruction or epistaxis. Mar 22, 20 juvenile nasopharyngeal angiofibroma jna is a rare, benign, highly vascular, and locally aggressive tumor that predominantly occurs in adolescent males. Article information, pdf download for juvenile nasopharyngeal. Due to aggressive local growth, skull base location and risk of profound hemorrhage, na is a challenge for surgeons. Nasopharyngeal angiofibroma naf is a highly vascular, histologically benign, but. Objective to develop a new staging system for juvenile nasopharyngeal angiofibroma that reflects changes in surgical approaches endonasal, route of intracranial extension, and the extent of vascular supply from the internal carotid artery. Facial palsy following embolization of a juvenile nasopharyngeal. Juvenile nasopharyngeal angiofibroma radiology reference. Juvenile nasopharyngeal angiofibroma a free powerpoint ppt presentation displayed as a flash slide show on id.
There are many classification described although none is. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for. Mar 07, 2020 it most commonly affects adolescent males and may grow into fissures of the. Imaging in the diagnosis of juvenile nasopharyngeal. However, the extensions of the tumor seem to be independent, each one with distinct behavior. They often grow quickly during puberty, then slow down or stop growing entirely after adolescence. Nasopharyngeal angiofibroma na is a rare, vascular tumor affecting adolescent males. Juvenile nasopharyngeal angiofibroma jna is a highly vascular, benign, yet locally invasive tumor that. Staging of juvenile nasopharyngeal angiofibromas is performed with crosssectional imaging and relies on the identification of local tumor extent, and invasion of adjacent spaces. To the best of the authors knowledge, this is the first case of angiofibroma with clinical followup after.
Juvenile nasopharyngeal angiofibroma jna is a benign tumor of the nasopharynx composed of fibrous connective tissue and an abundance of endotheliumlined vascular spaces. Nasopharyngeal angiofibroma symptoms aurora health care. Pdf an unusual case of epistaxisjuvenile nasopharyngeal. Endoscopic excision of juvenile nasopharyngeal angiofibroma. Due to aggressive local growth, skull base location and risk of profound hemorrhage, na is a challenge for. Because of technological advances both in surgery and radiology, management of jna patients has been refined. Juvenile nasopharyngeal angiofibroma with audio youtube. Nasopharyngeal angiofibroma an overview sciencedirect topics. Juvenile nasopharyngeal angiofibroma jna onset most commonly is in the second decade. Although the exact pathogenesis of the tumour is not yet known, natural history and growth patterns can be predicted. Anesthetic management of nasopharyngeal angiofibroma.
Juvenile nasopharyngeal angiofibroma jna is a rare, histologically benign skull base tumor that develops in adolescents and young. Juvenile nasopharyngeal angiofibroma with orbital extension. The nasopharyngeal angiofibroma is an aggressive, vascular tumor that may represent a challenge for the anesthesiologist by the risk of profuse bleeding. The treatment of choice is embolization followed by surgery. Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma. Biomolecular analysis of juvenile nasopharyngeal angiofibroma. Nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Angiofibromas have been sporadically described in extanasopharyngeal locations. Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor of the nasopharynx that arises from the superior margin of the sphenopalatine foramen and grows in the back of the nasal cavity. May 15, 2012 nasopharyngeal angiofibroma na is a rare, vascular tumor affecting adolescent males. The association of these two rare condi tions suggests that nasopharyngeal angiofibroma is an extracolonic manifestation of adenomatous pol yposis. Nasopharyngeal angiofibroma naf is a highly vascular, histologically benign, but sometimes locally aggressive tumor of the nasopharynx that occurs almost exclusively in males, usually between 10 and 20 years of age.
May 16, 2018 nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Intricate mixture of stellate and staghorn blood vessels with variable vessel wall thickness ranging from single layer of endothelium to variable smooth muscle coat. Vessels are thinwalled, lack elastic fibers, have absent or incomplete smooth muscle, and vary in appearance from stellate or staghorn to barely conspicuous because of stromal compression. This is a pdf file of an unedited manuscript that has been accepted for. Health, general endoscopic surgery complications and side effects patient outcomes endoscopy nasopharyngeal cancer care and treatment diagnosis risk factors. Ris zotero endnote bibtex medlars procite refworks reference manager mendeley. Ppt journal juvenile nasopharynx angiofibroma radiation. Juvenile nasopharyngeal angiofibroma jna is a benign tumor of the nasopharynx, which accounts for 0. Interphase fish on cut sections from nine additional cases of soft tissue angiofibroma using pools of bacs covering ahrr and ncoa2 yielded fusion signals in at least 10% of the nuclei in three cases. Nasal cavity, paranasal sinuses, nasopharynx nasopharyngeal angiofibroma. It most commonly affects adolescent males because it is a hormonesensitive tumor. Nasopharyngeal angiofibroma definition of nasopharyngeal. Nasopharyngeal angiofibroma purushothaman p k, ramakrishnan r, kiruthiga devi m department of ent, head and neck surgery, srm medical college hospital and research centre, srm university, srm nagar, potheri603203, kanchipuram district, tamilnadu, india abstract juvenile nasopharyngeal angiofibroma is a rare. Pdf juvenile angiofibroma jna is a relatively uncommon, highly vascular and benign tumor that.
Typical signs are nasal and eustachian tube obstruction, adenoidal speech, and dysphagia. Review article nasopharyngeal angiofibroma ashutosh hota s. It most commonly affects adolescent males and may grow into fissures of the. We aimed to report the characteristic magnetic resonance imaging mri findings and the spread patterns of jna. Plain filmno longer play a role in the work up of a suspected jna, however they may still be obtained in some instances during assessment of nasal obstruction, or symptoms of sinus obstructions. Juvenile nasopharyngeal angiofibroma jna is a locally aggressive benign vascular tumour exclusively amongst adolescence males. Juvenile nasopharyngeal angiofibroma jna is a rare benign tumor arising predominantly in the nasopharynx of adolescent males. A 52yearold man underwent surgery for nasopharyngeal angiofibroma after adjuvant radiofrequencyinduced thermotherapy. Angiofibroma nasofaring juvenile free download as pdf file. We report the case of a 17yearold male who presented in 1995 with a mass filling the left posterior nasal cavity. Involution of juvenile nasopharyngeal angiofibroma with. Seven cases of nasopharyngeal angiofibroma treated surgically have been reported.
Nasopharyngeal angiofibroma in patients with familial. Common practice is to excise the tumor with open or endoscopic surgery. In 1906 chareau revived the interest in the study of juvenile nasopharyngeal angiofibroma. Radiologists prior knowledge on the tumors characteristics aids in establishing a diagnosis. Jul 15, 2015 juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Additional interphase fish using a breakapart probe for the ncoa2 gene in the six fusionnegative cases did not reveal any split signals.
Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. It is an aggressive neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium. Although it can occur in all age groups, it is most common in adolescents and young adults between 14 and 25 years of age. Magnetic resonance imaging findings ayse gul alimli, murat ucar, cigdem oztunali, koray akkan, oznur boyunaga, cagr.
Ppt juvenile nasopharyngeal angiofibroma powerpoint. Linkpage citation abstract juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. Preoperative selective arterial embolization has decreased intraoperative blood loss and facilitated resection of larger tumors. Download pdf 2268k download meta ris compatible with endnote, reference manager, procite, refworks. Angiofibromas are small, reddish brown or even fleshcolored, smooth, shiny, 0. The pictures used in this presentation have been obtained from a number of sources. May 16, 2018 juvenile nasopharyngeal angiofibroma jna is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males. The juvenile nasopharyngeal angiofibroma has a characteristic growth in all directions from its origin.
Sep 01, 2008 juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males. To describe a case of the rare complication of facial palsy following. For a discussion of this entity please refer to the parent article. It is a rare, benign, vascular neoplasm that accounts for less than 0. Juvenile nasopharyngeal angiofibroma has been documented since the time of hippocrates 4 bc.
A rare case initially diagnosed as nasopharyngeal angiofibroma in an old patient and later diagnosed as pseudotumor by the careful histological and. Juvenile nasopharyngeal angiofibroma journal of the belgian. Endoscopic endonasal resection of juvenile nasopharyngeal. Though it is a benign tumor, it is locally invasive and can invade the nose, cheek, orbit. Review article nasopharyngeal angiofibroma ashutosh hota. Introduction uncommon, benign and extremely vascular tumour up to 0. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. Infact hippocrates goes on to describe a polyp in the nose which weeped blood.
Their use is purely for academic and teaching purposes. Juvenile nasopharyngeal angiofibroma jna javiers story. Jnas occur almost exclusively in the nasopharynx of adolescent. The name of the disease is derived from the fact that it occurs during adolescence, almost exclusively in boys. Transnasal endoscopic resection of juvenile nasopharyngeal.
Juvenile nasopharyngeal angiofibroma jna is a rare, benign, highly vascular, and locally aggressive tumor that predominantly occurs in adolescent males. Angiography showed arterial supply mainly from the right external carotid artery, but also from the right internal carotid artery and the left external carotid artery. To present the outcome of excision of juvenile nasopharyngeal angiofibroma. We report the case of a years old, 52 kg, asa1, who was scheduled for the resection of an angiofibroma invading facial sinuses and internal carotid artery, and submitted to external carotid and internal maxillary arteries embolization one. Aug 16, 2008 nasopharyngeal angiofibroma presents with symptoms of nasal obstruction and epistaxis. The typical patient is an adolescent male with a clinical history of recurrent epistaxis and nasal obstruction. The typical symptoms of juvenile nasopharyngeal angiofibroma are chronic nasal. This book, the first of its kind devoted to the management of this tumor, is based on dr. The tumor usually arises in puberty and is more common in boys than in girls. Other titles eg, nasopharyngeal fibroma, bleeding fibroma of adolescence, fibroangioma have also been used. A new endoscopic staging system for angiofibromas oncology. A juvenile nasopharyngeal angiofibroma jna is a noncancerous tumor made up of blood vessels that grow at the posterior aspect of the nose.
In spite of two attempts at resection of the tumor and arterial embolization, the tumor progressed. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that predominantly occurs in adolescent males, the average age of occurence. Juvenile nasopharyngeal angiofibroma electronic journal of. Pdf juvenile nasopharyngeal angiofibroma researchgate. It is the most common benign tumor of the nasopharnyx but only accounts for less than 0.
Adolescents and young adults between 14 and 25 years are affected, and there is a distinct male predominance. Javier and his family share their experience at johns hopkins medicine, after seeking treatment following a diagnosis of a juvenile nasopharyngeal angiofibroma jna tumor. Juvenile nasopharyngeal angiofibromas staging radiology. Imaging in the diagnosis of juvenile nasopharyngeal angiofibroma article pdf available in journal of clinical imaging science 3suppl 1. Juvenile nasopharyngeal angiofibroma jna is a rare tumor that predominantly occurs in adolescent males, the average age of occurence being 15. Juvenile nasopharyngeal angiofibroma jna is a benign tumor of the nasopharynx composed of fibrous. Jan 08, 2018 javier and his family share their experience at johns hopkins medicine, after seeking treatment following a diagnosis of a juvenile nasopharyngeal angiofibroma jna tumor. Plain radiographs no longer play a role in the workup of a suspected juvenile nasopharyngeal angiofibroma, however they may still be obtained in some instances during the assessment of nasal obstruction, or symptoms of sinus obstructions. Pdf download for facial palsy following embolization of a juvenile. The differential diagnosis of juvenile nasopharyngeal angiofibroma includes nasal polyp with. To the best of the authors knowledge, this is the first case of angiofibroma with clinical followup after thermocoagulation.
Radiofrequencyinduced thermotherapy of nasopharyngeal. Transnasal endoscopic resection of juvenile nasopharyngeal angiofibroma without preoperative embolization. Juvenile nasopharyngeal angiofibroma is a rare benign tumour of vascular origin found in adolescent males, originating around the sphenopalatine foramen. We had recently a case of an extensive jna in the r nasal cavity extending from the anterior nares to the nasopharynx involving the rt pterygopalatine. Nasopharyngeal angiofibroma an overview sciencedirect. The upmc staging system for juvenile nasopharyngeal angiofibroma accounts for 2 important prognostic factors, route of cranial base extension, and vascularity and is applicable to endoscopic or open. Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns.
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